Toward mechanistic virtual immune cells
Nature Biotechnology · 44, 1089–1091 · 2026
Considers how molecular mechanisms can inform the development of virtual models of immune cells.
Publications by our affiliated researchers
These publications present research by members of our coalition. NPC brings these researchers together to exchange ideas, tools, and methods, support one another’s work, and advance our shared mission of a better future for normal people.
Journal publications
2026
Scalable discovery and validation of order-specific electronic health record event trajectories for interpretable adverse-outcome risk estimation
Journal of Biomedical Informatics · 177, 105008 · 2026
Develops an interpretable method for identifying ordered health-event sequences associated with the risk of later adverse outcomes.
Earlier preprint (medRxiv, 2025): Trajectories matter: Discovery and validation of ordered EHR sequences that inform clinical risk predictions.
MENDELSEEK: An algorithm that predicts mendelian genes and elucidates what makes them special
PLOS Computational Biology · 22(2), e1013992 · 2026
Predicts genes associated with Mendelian disease and examines the properties that distinguish them.
2025
Entabolons: How Metabolites Modify the Biochemical Function of Proteins and Cause the Correlated Behavior of Proteins in Pathways
Journal of Chemical Information and Modeling · 65(11), 5785–5800 · 2025
Examines how metabolites can influence protein function and connect the behavior of proteins within biological pathways.
Valsci: an open-source, self-hostable literature review utility for automated large-batch scientific claim verification using large language models
BMC Bioinformatics · 26, 140 · 2025
Introduces open-source software that uses large language models to evaluate scientific claims against published literature.
A mode of action protein based approach that characterizes the relationships among most major diseases
Scientific Reports · 15, 9668 · 2025
Groups diseases by their predicted protein mechanisms to investigate shared biology across disease categories.
2019
SOX4 regulates invasion of bladder cancer cells via repression of WNT5a
International Journal of Oncology · 55(2), 359–370 · 2019
Examines how SOX4 affects the invasive behavior of bladder cancer cells, including its relationship with WNT5a expression.
Preprints
A reliability-screened thalamocortical control-network phenotype tracks cocaine-use history in cocaine use disorder
medRxiv · Posted April 29, 2026 · 2026
Investigates the reliability of resting-state brain-network measures and their associations with cocaine-use history.
Publication records checked September 17, 2026. Meet our people